Career Opportunities with Seres Therapeutics, Inc.

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Careers At Seres Therapeutics, Inc.

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Scientist, Molecular Technology

Department: Molecular Technology
Location: Cambridge, MA

Why Seres Therapeutics

At Seres Therapeutics, we have a singular mission to transform the lives of patients by targeting the underlying cause of their diseases.  We are pioneers and explorers, charting a new course.  You’ll have the opportunity to truly define your area of focus.

If you have a pioneering spirit, join us as we ignite a revolution in the treatment of disease through the microbiome.

What’s Your Mission?

In this role, you will have the opportunity to drive the development of molecular and genomics methods to support the discovery and development of microbiome therapeutics. By rigorously examining details of these workflows, you will understand, define, and improve our molecular toolset to assay microbes and microbial communities. You will play a critical role in the development of Ecobiotic therapeutic products for delivery to patients as well as the advancement of the company’s discovery platforms for the identification and design of Ecobiotic candidates.

What You’ll Do

  • Oversee the design, development, qualification and validation of molecular-based assays to support the characterization of complex microbial communities and defined compositions of microbes
  • Develop and use qualitative and quantitative assays to define parameters of sample preparation and NGS library construction steps for a broad range of clinical and non-clinical samples 
  • Work directly with our bioinformatics and microbiome sciences groups to understand how various sequencing methodologies and library construction workflows directly impact gut microbiome characterization and our in-house data analysis pipelines
  • Work directly with our external vendors as a technical expert in the field
  • Collaborate closely with the Bioprocess, Clinical, and Quality groups to develop, prototype, and validate molecular- and genomic-based QC and clinical assays
  • Stay current with literature to enable the company to stay abreast of the most recent science and ‘omic methods for the characterization of microbial strains and populations

What You’ll Bring

  • Technical knowledge and hands-on experience with molecular biological methods such as DNA & RNA purification, enzymatic manipulation of DNA & RNA, PCR, qPCR, sequencing, molecular cloning, library construction, etc
  • Creativity, scientific curiosity, and the desire and ability to both evaluate and leverage existing technologies and develop novel approaches as needed
  • Familiarity with next-generation sequencing technologies and associated workflows
  • Experience in the analysis of microbial populations and microbial genomics
  • Excellent interpersonal and collaborative skills
  • Ability to work independently and take initiative in a highly dynamic environment
  • PhD in relevant field with 0-2 years of experience

You May Also Bring

  • Proficiency in troubleshooting, protocol development, and vendor management
  • Direct experience in NGS sample prep workflows strongly preferred
  • Good working knowledge in the field of analytical microbiology
  • Experience with flow cytometry, FISH, Nanostring, lab automation or related technologies a plus

Who We Are

Seres Therapeutics is a clinical stage biotherapeutic company focused on discovering and developing Ecobiotic™ therapeutic products, novel drugs to treat important diseases by targeting the underlying biology of the human microbiome.  Founded by Flagship VentureLabs, Seres is pioneering the first therapeutics that catalyze a shift to health by augmenting the biology of the microbiome.  Current candidates span infectious, metabolic, and inflammatory diseases.  For more information, please visit

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